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Community-acquired pneumonia is a commonly diagnosed illness in which no causative organism is identified in half the cases. Application of molecular diagnostic techniques has the potential to lead to more targeted therapy in the face of increasing antibiotic resistance.

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

No potential conflict of interest relevant to this article was reported.

We thank Drs. Thomas M. File and John G. Bartlett for their critical review of an earlier version of this manuscript and for their insightful comments.

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Source: http://www.nejm.org/doi/full/10.1056/NEJMra1312885


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